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Bioprocess

Every bioprocess consists of upstream & downstream processes. Upstream processing refers to the stages involved in producing our desired product, bioactive peptides, from our chosen cell line which is a combination of pronase and salt active nuclease in a bioreactor. Following on from the production of our product recovery & purification steps are necessary to isolate our product & ensure it is of desired quality which is essentially referred to as the downstream end of bioprocessing.​

Upstream
Process

This involves the extraction of the bioactive peptides from the meat waste. It includes homogenization, preparation of the bioreactor and enzyme hydrolysis.

Downstream
Process

This involves the purification and recovery of the bioactive peptides. It includes ultrafiltration, size exclusion, ion exchange & hydrophobic interaction chromatography stages and bioactive assays

Scope

The aim of the bioprocess we have designed & developed is to produce natural bioactive peptides with ACE inhibitory properties from protein-rich meat waste which can be used to treat hypertension without the side effects associated with current synthetic drugs. In this way, we are fully utilizing waste resources to produce medicinally important products while simultaneously decreasing the burden of waste management and financially benefitting the meat industry.

 

The main stages involved in our bioprocess are:

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Figure 6. Flow chart of our bioprocessing stages

Watch our bioprocess in action!

Our Bioreactor

Click to explore the different parts of our bioreactor and their role in the bioprocess:

Vessel
Gauge
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